1 Exposure has been defined in various ways in the past. For example, and Institute of Medicine report (IOM, 1994) defines exposure as "the concentration of an agent in the environment in close proximity to a study subject." Clearing the Air: Asthma and Indoor Air Exposures (2000), Institute of Medicine. 2 The presence of some biological agents in cabin air, primarily airbome allergens, has also raised questions. Exposures to allergens (e.g., cat dander) have been reported to cause health effects, but have not been definitively documented in aircraft. Transmission of infectious agents from person to person has been documented to occur in aircraft, but the most important transmission factors appear to be high occupant density and the proximity of passengers. Transmission does not appear to be facilitated by aircraft ventilation systems. The Airliner Cabin Environment and the Health of Passengers and Crew (2002), Board on Environmental Studies and Toxicology. 3 To answer specific questions about cabin air quality, a research program should be established. The committee considers the following research question to be of high priority: [...] - Outside-air ventilation. Does the ECS provide sufficient quantity and distribution of outside air to meet the FAA regulatory requirements (FAR 25.831), and to what extent is cabin ventilation associated with complaints from passengers and cabin crew? Can it be verified that infectious-disease agents are transmitted primarily between people in close proximity? Does recirculation of cabin air increase cabin occupants' risk of exposure? The Airliner Cabin Environment and the Health of Passengers and Crew, Board on Environmental Studies and Toxicology. 4 The necessity of contact or proximity to the target is another distinguishing feature of mines. APL are directly activated by contact, typically the pull of a trip wire. In AT mines, the magnetic field generated by an armored vehicle influence. Acoustic signatures can also arm firing circuits. Infrared can be used to detect the presence of a target within the mine's range and fire the main charge. Antihandling devices can be incorporated to preclude easy removal or neutralization. Alternative Technologies to Replace Antipersonnel Landmines (2001), Commission on Engineering and Technical Systems. 5 One of the key differences between traditional supply chains and highly integrated supply chains is the degree of proximity between members and the resulting differences in the efficiency of joint operations. Geographic and cultural proximity traditionally provided business advantages for SMEs, many of whom served only local customers and had to compete only against other local suppliers. Globalization, electronic communications, and modern shipping capabilities now enable suppliers from all over the world to compete for local business. Large suppliers can typically afford proximity capabilities that SMEs cannot, including plant sited near their customers and skills in dealing with different cultures. To remain competitive, SMEs may have to improve their organizational, cultural and geographic proximity to serve an increasingly widespread customer base. Organizational proximity can take several forms including membership in joint project teams or the placement of employees in one another's faculties. Cultural proximity, which typically evolves over time, can be achieved through the adoption of common business practices, jargon, ethical standards, and language. Cultural proximity is especially important for doing business with customers from different countries and cultures. The dividends of cultural proximity can include repeat business, loyalty, and assistance in problem solving during times of crisis. Geographic proximity may involve locating supplier facilities adjacent to OEM operations. For example, long-term relations between beverage producers and container manufacturers led container suppliers to locate their fabrication plants adjacent to breweries. Cans are drawn, finished, and moved on conveyors through a common wall into the brewery where they are filled, sealed, packed, and shipped, all without human contact. Proximity in an international supply chain can require investments in metric dimensioning, compliance with international standards, and participation in international trade fairs, such as the one held annually in Hanover, Germany. Partnerships with foreign companies can be used by SMEs to obtain cost-effective access to foreign markets and sources of supply. Surviving Supply Chain Integration: Strategies for Small Manufactures (2000), Commission on Engineering and Technical System 6 Because Internet technologies and modern transportation capabilities enable suppliers from low-wage areas to compete effectively with U.S. small and medium -sized manufacturing enterprises (SMEs), pressure on SMEs to improve their cultural, organizational, and geographic proximity to their customers and suppliers has increased. Even SMEs with limited resources can respond to some of these challenges at low cost through increased cultural education and use of the Internet and Worldwide Web. Surviving Supply Chain Integration: Strategies for Small Manufactures (2000), Commission on Engineering and Technical Systems "Proximity" Passages CVA Think-Aloud Protocols